Vitamin D Shots – The IM Shot Series

This week’s IM shot highlight is for Vitamin D! Vitamin D is an important vitamin that people are commonly deficient in, especially during the winter time. Though there are vitamin d rich foods, most vitamin D intake is from being in the sun – thus the difficulty of getting vitamin d in the winter months when there is less sunshine. Read more to see if vitamin D shots are a viable option for you!

Table of Contents

The Definition:

A vitamin D shot is an intramuscular shot of vitamin D3. You’ll likely notice vitamin D2 supplements are available as well; however, at Drp IV, we use vitamin D3 because it is better absorbed by the body.

An intramuscular shot is when the vitamin, or sometimes medication, is injected into muscle tissue in order to promote rapid absorption, increased bioavailability, and quicker onset of benefits. IM shots are very quick and take around 5 minutes for a nurse to prep and administer. Vitamin D isn’t the only vitamin we offer in IM shot form, however, it is a popular one because vitamin D isn’t one we administer in a drip.

What are the benefits of vitamin D shots?

Here are a few of the major benefits that vitamin D shots can offer:


Strong bones – Vitamin D shots promote strong bones through enhanced calcium absorption.

Healthy cardiovascular system – They support a healthy cardiovascular system, potentially reducing related risks.

Immune boost – Vitamin D boosts the immune system, aiding in defense against infections.

Improved mood – These shots contribute to improved mood regulation, potentially alleviating symptoms of depression.

Cognitive health – They positively impact cognitive health, potentially reducing the risk of cognitive decline.


Vitamin D plays a role in many bodily functions so it’s important to have enough of it. However, if someone is deficient, they’ll experience some of these negative side effects that vitamin D shots can help with: 


  • Fatigue
  • Weak bones
  • Weight gain
  • Sleep issues
  • Headaches
  • Depression symptoms
  • Digestive problems

Vitamin D Shot vs IV

A glutathione shot is a relatively safe procedure and shouldn’t cause side effects if properly administered and in the correct dosage. However, every person is different and could have a different experience with adverse effects. If too much glutathione is given, patients can experience the following:


  • Site reactions such as redness, swelling, or pain
  • Allergic reactions
  • Nausea or stomach cramps
  • Headaches


Keep in mind, glutathione is safe for most people but if you experience any of these side effects, consult with your primary care physician.

IM Shot or IV Infusion? Which is the Better Method?

Both are great methods of getting vitamin D; however one may work better than the other depending on an individual’s situation. At Drp IV, we only offer vitamin D as an IM shot but you may see other IV therapy providers that offer it in an IV. Here are some important differences to consider and be aware of.


Administration Process:


Vitamin D Shots: Administered subcutaneously, meaning under the skin and in this case, directly into the muscle.

IV: In contrast, IV administration delivers vitamin D directly into the bloodstream through a vein. It is administered with saline and often paired with other vitamins.


Absorption Speed:


Vitamin D Shots: Absorption occurs slightly more gradually as the vitamin is released into the bloodstream over time. Because it is an injection though, the absorption is still very fast and comparable to an IV.

IV: IV administration offers a slightly faster absorption rate, making it an efficient option for those seeking quick results. 


Frequency of Administration:


Vitamin D Shots: Typically administered at regular intervals, such as weekly or monthly, depending on the prescribed dosage and individual health goals.

IV: Frequency may vary, but IV administration is often reserved for specific cases or individuals with conditions that require extra hydration or other vitamins as well.


Comfort and Convenience:


Vitamin D Shots: Generally considered convenient and with minimal discomfort during the injection process. These shots are very quick and only take a couple of seconds.

IV: An IV will certainly take longer than an IM shot so overall this method of administration is not as convenient. There is minimal discomfort but the treatment does take longer than a quick shot so any discomforts felt during the IV will continue throughout the treatment.

Common Questions about Vitamin D Shots

Are vitamin D shots good for you?

Generally, yes! Vitamin D is an essential nutrient. Deficiencies in vitamin D can cause very unpleasant side effects so it’s important to get enough. However, you can definitely overdo vitamin D and experience adverse effects of getting too much as well. 600-800 UIs a day are standard.

At Drp IV, each of our intramuscular shots are $35, including the vitamin D shots.

Yes. Vitamin D shots are administered directly into the muscle which significantly increases the bioavailability of the vitamin. If you’re looking to replenish your vitamin D fast, it is also a better route to go because the body is able to absorb it much faster.

When you go through Drp IV, we have medical providers who write a prescription for your treatment.

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Drip Admin

Drip Admin has written several informative articles and guides on the benefits of IV therapy, emphasizing the science behind the practice. Our writing style is engaging, concise, and accessible, making complex medical concepts easily understandable for readers.

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